My overarching aim is to identify how signaling at the synapse, circuit and network levels shape behaviour and orchestrate disease. This is especially important for treatment of complex neurological and neurodevelopmental diseases where brain receptor defects result in severe and debilitating symptoms and we do not currently have any credible therapy.
The inherent complexity of such a venture undoubtedly requires an interdisciplinary approach and equipped with training spanning multiple domains of biology, biophysics and computation. I am addressing key questions in cellular biology, neuroscience and pharmacology with relevance to multiple disorders such as epilepsy, intellectual disability, Down syndrome, Rett syndrome and autism.
My research falls into two main domains: basic and disease neurobiology. In this website you will find more details of our work carried out at University College London and Harvard University over the years.
If you have any questions please feel free to reach out.
Saad Hannan 